3- or 4-substituted oxotremorine derivatives and a method of tre

Details 3- or 4-substituted oxotremorine derivatives and a method of tre 3- or 4-substituted oxotremorine derivatives and a method of tre

1990-08-22

1992-02-18

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514326, 514 63, 548518, 548524, 548110, 548550, 546 16, 546208, C07D20738, C07D40306, C07D 3140

Patent

active

050895184

ABSTRACT:
This disclosure describes novel 3 or 4 substituted oxotremorine derivatives having polar substituted oxygen or sulfur groups. The compounds have cholinergic activity. Also disclosed are methods for treating diseases of the central nervous system in mammals employing the compounds, pharmaceutical preparations containing the compounds and processes for the production of the compounds.

REFERENCES:
patent: 3041351 (1962-06-01), Nutting
patent: 4325945 (1982-04-01), Matarajan et al.
patent: 4410542 (1983-10-01), Iwan et al.
patent: 4937235 (1990-06-01), Trybulski et al.
Kauhi-Eldeen-Iraqui J. Sci., vol. 18, (1977), pp. 70-75.

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