3- or 4-substituted oxotremorine derivatives and a method of tre

Details 3- or 4-substituted oxotremorine derivatives and a method of tre 3- or 4-substituted oxotremorine derivatives and a method of tre

1990-02-20

1990-08-28

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514428, 548541, 548556, C07D20712, A61K 3140

Patent

active

049526006

ABSTRACT:
This disclosure describes novel 3 or 4 substituted oxotremorine derivatives having polar substituted oxygen or sulfur groups. The compounds have cholinergic activity. Also disclosed are methods for treating diseases of the central nervous system in mammals employing the compounds, pharmaceutical preparations containing the compounds and processes for the production of the compounds.

REFERENCES:
patent: 4243672 (1981-01-01), Barnish et al.
patent: 4536500 (1985-08-01), Bourgery et al.
patent: 4847284 (1989-07-01), Schwartz et al.

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