3- or 4-substituted oxotremorine derivatives

Details 3- or 4-substituted oxotremorine derivatives 3- or 4-substituted oxotremorine derivatives

1989-01-23

1990-06-26

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Silicon containing doai

514326, 514443, 548406, 548544, 548519, 548520, 548524, 546 14, 546208, A61K 31675, A61K 31040, C07D20708

Patent

active

049372351

ABSTRACT:
This disclosure describes novel 3 or 4 substituted oxotremorine derivatives having polar substituted oxygen or sulfur groups. The compounds have cholinergic activity. Also disclosed are methods for treating diseases of the central nervous system in mammals employing the compounds, pharmaceutical preparations containing the compounds and processes for the production of the compounds.

REFERENCES:
B. Ringdahl, J. Med. Chem., "5-Methyl-2-pyrridone Analogues of Oxotremorine as Selective Muscarinic Agonists," 31(3), pp. 683-688 (1988).
J. Levy, et al., C. R. Acad. Sci., Paris, Ser. D., "Comparison in mice . . . ", 264(18), pp. 2250-2253 (1967).
J. Levy, et al., Chemical Abstracts 67:52609h, "Central and peripheral cholinergics and anticholinergics," (1967).
J. Levy, et al., Chemical Abstracts 68:103538q, "Central and Peripheral Cholinergics and anticholinergics, " (1968).

Affiliated with

Also associated with

Rating

3- or 4-substituted oxotremorine derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3- or 4-substituted oxotremorine derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3- or 4-substituted oxotremorine derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1125664