3'-O-aminoacyl ARA uridines, method of making, and antiviral act

Details 3'-O-aminoacyl ARA uridines, method of making, and antiviral act 3'-O-aminoacyl ARA uridines, method of making, and antiviral act

1996-07-10

1998-01-06

Kight, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 50, 536 2711, 536 274, 536 2854, A61K 3170, C07H 1909

Patent

active

057054924

ABSTRACT:
Pyrimidine nucleoside derivatives of formula ##STR1## wherein R.sup.1 represents aryl, R.sup.2 represents lower alkyl, R.sup.3 represents an acyl group derived from an amino acid and R.sup.4 represents hydrogen or fluorine and the asterisk denotes that the configuration at the carbon atom indicated thereby is (S) or (R),
are disclosed. These compounds, as well as their salts, are useful as antiviral agents.

REFERENCES:
patent: 4851519 (1989-07-01), Lambert et al.
patent: 5010060 (1991-04-01), Lambert et al.

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