3-Nitropyrazole derivatives

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424273P, C07D23116

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active

042359953

ABSTRACT:
Novel 1,4-disubstituted-3-nitropyrazoles having antimicrobial, parasiticidal, and herbicidal activity are prepared by a reaction sequence of which the individual steps are conventional. The new 3-nitropyrazoles are characterized by a 1-substituent and a usually carbonyl-containing 4-substituent. The novel 3(5)-nitro-4-pyrazolecarbonitrile is obtained as an intermediate in the preparation of the biologically-active compounds. Preferred compounds are 1-alkyl or -alkenyl-4-pyrazolecarboxamides are carbonitriles. The new compounds are particularly useful for the control of bacterial animal diseases.

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patent: 3234217 (1966-02-01), Schmidt et al.
patent: 3658839 (1972-04-01), Kiehne et al.
patent: 3719759 (1973-03-01), Sarett et al.
Cheng, J. Hetero. Chem. 1968, vol. 5, pp. 195-197.

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