3-Nitro-4-bromomethyl benzoic acid

Details 3-Nitro-4-bromomethyl benzoic acid 3-Nitro-4-bromomethyl benzoic acid

1977-11-10

1980-02-19

Helfin, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C07C 7946

Patent

active

041896050

ABSTRACT:
The invention is addressed to the preparation of 3-nitro-4-bromomethyl benzoic acid, as a new compound from which 3-nitro-4-bromomethyl benzoyl amide polystyrene resin can be prepared for solid synthesis of protected peptide acids and amides and separation thereof without cleavage of acid labile protecting groups or decomposition of aromatic acid groups and from which purified polypeptides can be formed.

REFERENCES:
Hoffman, Chemical Abstracts, vol. 63, 6901(e), 1965.
Beilsteins Handbuch der Organischen Chemie, 14, 489, Sep. No. 1905 (1931).
Beilsteins Handbuch der Organischen Chemie, 9, 504, Sep. No. 941 (1926).

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