3-Nitro-1-phenyl-1-(m-chlorophenyl)-propan-2-ol.

Details 3-Nitro-1-phenyl-1-(m-chlorophenyl)-propan-2-ol. 3-Nitro-1-phenyl-1-(m-chlorophenyl)-propan-2-ol.

1980-06-03

1982-04-27

Hines, Robert V.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

26050118, 564319, C07C 400

Patent

active

043272282

ABSTRACT:
A process for the preparation of 3-dimethylamino-1-phenyl-(m-chlorophenyl)propan-2-ol and its salts which comprises the Raney nickel catalysed reduction of 3-nitro-1-phenyl-(1-m-chlorophenyl)propan-2-ol with simultaneous or subsequent dimethylation and thereafter, if desired, salification.

REFERENCES:
patent: 1356877 (1920-10-01), Nagai
patent: 1973647 (1934-09-01), Nagai
patent: 3431272 (1969-03-01), Loev
patent: 3859354 (1975-10-01), Booher et al.
patent: 3932663 (1976-01-01), Barrett
Henning et al., "Helv. Chim. Acta.," vol. 59, No. 6, pp. 2213-2217 (1976).
Houben-Weyl, "Methoden der Organischen Chemie", vol. 11, No. 1 pp. 385-391 (1957).
Wagner et al., "Synthetic Organic Chemistry", p. 664 (1953).
Rainer et al., "Chemical Abstracts", vol. 85, p. 465, Section No. 1767544 (1976).

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