3-N-Pyridinium nocardicin and antibiotic composition thereof

Details 3-N-Pyridinium nocardicin and antibiotic composition thereof 3-N-Pyridinium nocardicin and antibiotic composition thereof

1979-08-01

1981-04-21

Randolph, John D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602454, 424251, 424256, 424266, 424270, 424272, 424273R, 544321, 544323, 544326, 544329, 544330, 544332, 546 14, 546112, 546138, 546270, 546275, A61K 3144, A61K 31445, C07D21389, C07D21379

Patent

active

042633060

ABSTRACT:
This invention relates to a new class of antibiotics (I): ##STR1## wherein the stylized radical (hereafter referred to as R'): ##STR2## attached to the 3-amino nitrogen of nocardicin represents a mono- or polycyclic N-containing heterocyclic group; R is, inter alia, hydrogen, substituted and unsubstituted: alkyl, aryl, alkenyl, heterocyclylalkyl, heterocyclylalkenyl, aralkenyl, aralkyl, --NR.sub.2, COOR, CONR.sub.2, --OR, or CN.

REFERENCES:
patent: 3842072 (1974-10-01), Hevsler et al.
patent: 4144232 (1979-03-01), Koppel et al.
patent: 4195021 (1980-03-01), Herron
March, J., Advanced Organic Chemistry: Reactions, Mechanisms and Structure, McGraw Hill, New York 1968, p. 502.

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