3-[N-aroyl(or thioaroyl)aminomethyl]-3-quinuclidinols

Details 3-[N-aroyl(or thioaroyl)aminomethyl]-3-quinuclidinols 3-[N-aroyl(or thioaroyl)aminomethyl]-3-quinuclidinols

1991-04-29

1992-08-11

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546137, C07D45302, A61K 31435

Patent

active

051378957

ABSTRACT:
3-[N-Aroyl(or thioaryol)aminoalkyl]-3-quinuclidinols corresponding to the formula: ##STR1## wherein X is O or S, and Ar is phenyl, substituted phenyl, indole, indazole or pyrimidine; optical isomers and the pharmaceutically acceptable acid addition salts and solvates thereof. These compounds have gastric emptying, antiemetic, anxiolytic and selective serotonin modulating or inhibiting activity.

REFERENCES:
patent: 4593034 (1986-06-01), Munson, Jr. et al.

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