3-methylidenyl-2-indolinone modulators of protein kinase

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S343000, C514S235500, C548S486000, C546S278400, C544S144000

Reexamination Certificate

active

06855730

ABSTRACT:
The present invention relates to novel 3-methylidenyl-2-indolinone compounds and physiologically acceptable salts and prodrugs thereof which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.

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