3-methoxy-4-hydroxyphenylglycol fluorescence polarization immuno

Details 3-methoxy-4-hydroxyphenylglycol fluorescence polarization immuno 3-methoxy-4-hydroxyphenylglycol fluorescence polarization immuno

1992-09-03

1994-12-13

Scheiner, Toni R.

Chemistry: analytical and immunological testing

Involving producing or treating antigen or hapten

Producing labeled antigens

436543, 436822, 530363, 530807, 549223, 549225, 536 41, A61K 39385, G01N 33533

Patent

active

053729498

ABSTRACT:
The present invention is directed to a fluorescence polarization immunoassay for determining the 3-methoxy-4-hydroxyphenylglycol content in body fluids, to the various components needed for preparing and carrying out such an assay, and to methods of making these components. Specifically, tracers, immunogens and antibodies are disclosed, as well as methods for preparing them. The assay is conducted by measuring the degree of polarization of plane polarized light that has been passed through a sample containing antiserum and tracer.

REFERENCES:
patent: 4510251 (1985-04-01), Kirkemo et al.
patent: 5145791 (1992-09-01), Zeitvogel et al.
Keeton Science 211 pp. 586-588 (1981), "Specific and Sensitive Radioimmunoassay for 3-Methoxy-4-hydroxyphenylethyleneglycol (MOPEG)."

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