3-L-(5-thioxo-L-prolyl)thiazolidine-4-carboxylic acid and deriva

Details 3-L-(5-thioxo-L-prolyl)thiazolidine-4-carboxylic acid and deriva 3-L-(5-thioxo-L-prolyl)thiazolidine-4-carboxylic acid and deriva

1991-01-16

1993-05-18

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

548201, C07K 506, A61K 3702

Patent

active

052121607

ABSTRACT:
3-L-(5-thioxo-L-prolyl)thiazolidine-4-carboxylic acid and the derivatives thereof have valuable immunostimulating, antioxidant, antiradical and antiageing properties. They are prepared by thionating the corresponding 3-L-pyroglutamyl-L-thiazolidine-4-carboxylic acid derivatives or by condensing 5-thioxo-L-proline with the corresponding L-thiazolidine-4-carboxylic acid derivatives.

REFERENCES:
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patent: 5066644 (1991-11-01), Poli
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Fassina et al; Naunyn-Schiedeberg's Arch. Pharmacol. 222, 330, 1985.
2-Mammalian Hormones 104, 1986 162227x.
2-Mammalian Hormones 87, 104, 1986, 62252h.

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