Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1974-02-07
1977-01-04
Gotts, Lewis
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260295B, 2602949, 424274, C07D20946
Patent
active
040012719
ABSTRACT:
Isoindolin-1-one derivatives carrying on the nitrogen atom in the 2-position a phenyl or pyridyl radical, optionally carrying one or two substituents selected from halogen, alkyl (C.sub.1 -C.sub.4), alkoxy (C.sub.1 -C.sub.4), cyano and trifluoromethyl, and in the 3-position a grouping --O--T--NR.sub.1 R.sub.2 wherein T is alkylene (C.sub.2 -C.sub.6), and R.sub.1 and R.sub.2 represent hydrogen or alkyl (C.sub.1 -C.sub.4), are new compounds possessing pharmacodynamic properties and are useful as anti-arrhythmic agents.
REFERENCES:
patent: 3818011 (1971-06-01), Challier et al.
patent: 3898232 (1975-08-01), Cotrel et al.
Usov et al., "Chem. Abstracts," vol. 72, p. 370, No. 90230p, (1970).
Cotrel Claude
Jeanmart Claude
Messer Mayer Naoum
Gotts Lewis
Rhone-Poulenc S.A.
Williams S. P.
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