3-Indolyl-tertiary butylaminopropanols

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...

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26032612R, 26032615B, 26032615, A61K 3140, C07D20912, C07D20914

Patent

active

042345952

ABSTRACT:
1-Phenoxy-3-[(3-indolyl)-tert.-butyl]amino-2-propanols and related 1-aryloxy compounds are antihypertensive agents having vasodilator and adrenergic .beta.-receptor blocking action. Preferred compounds bear an ortho-substituent in the phenoxy group, and most preferably the cyano group.

REFERENCES:
patent: 2908691 (1959-10-01), Robinson
patent: 3328417 (1967-06-01), McLoughlin et al.
patent: 3852291 (1974-12-01), Augstein et al.
Van Arman et al. J. Pharm. & Exp. Therap. 133 Jul. 1961 pp. 90-97.
Jackman et al. J. Pharm. Pharmacol, 17, pp. 742-746 (1965).

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