3-Imidazolium cephalosporin derivatives

Details 3-Imidazolium cephalosporin derivatives 3-Imidazolium cephalosporin derivatives

1988-03-25

1990-03-06

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540222, A61K 31545, C07D50138

Patent

active

049066234

ABSTRACT:
A cephalosporin compound substituted by imidazolium ring in 3-position of cephem having the following formula (I), and pharmaceutically acceptable salt thereof, ##STR1## wherein R.sup.1 is an organic residue known in .beta.-lactam antibiotics, R.sup.2 is hydrogen atom or methoxy, n is 0 or 1, A is a nitrogen-containing group constituting imidazolium ring, is useful as an agent for preventing and treating bacterial infections.

REFERENCES:
patent: 4665065 (1987-05-01), Miyake
patent: 4698336 (1987-10-01), Saito
patent: 4788185 (1988-11-01), Miyake

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