3-(hydroxymethyl)-isoquinoline derivatives

Details 3-(hydroxymethyl)-isoquinoline derivatives 3-(hydroxymethyl)-isoquinoline derivatives

1987-05-20

1988-11-15

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 90, C07D21716

Patent

active

047851040

ABSTRACT:
This invention relates to new 3-(hydroxymethyl)-isoquinoline derivatives of the general formula (I), their acid addition salts, and to a process for the preparation thereof, furthermore to pharmaceutical compositions containing the same, ##STR1## wherein R and R.sup.1 are identical or different and stand for a hydrogen or halogen atom, a nitro or a C.sub.1-4 alkoxy group,

REFERENCES:
Valette, "Chemical Abstracts", vol. 79, 1973, Col. 5277m.
Lucas, Organic Chemistry, 2nd Ed., 1953, Amer. Book. Co., N.Y., pp. 213-227.
J. Chem. Soc., 1951, pp. 1951-1949.
Helv. Chim. Acta 31, 1978 (1948).
J. Am. Chem. Soc. 72, 1118 (1950).

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