3-Hydroxymethyl-7.beta.-(2-alkoxy-or benzyloxyimino-2-arylacetam

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

424246, C07D50132, C07D50134

Patent

active

040339505

ABSTRACT:
The invention provides novel antibiotic compounds which are 7.beta.-acylamidoceph-3-em-4-carboxylic acids, and non-toxic derivatives thereof characterized in that the acylamido group has the structure ##STR1## where R is a hydrogen atom or an organic group and R.sup.a is an etherifying monovalent organic group linked to the oxygen atom through a carbon atom. The compounds are syn isomers or exist as mixtures containing at least 75% of the syn isomer. These antibiotic compounds possess high antibacterial activity against a range of gram positive and gram negative organisms coupled with particularly high stability to .beta.-lactamases produced by various gram negative organisms. The invention is also concerned with the administration of the compounds.

REFERENCES:
Gregson et al., Chem. Abst., vol. 77; 126, 662a, (Abst. of L).
Cook et al., Ibid. vol. 78; 58,444z, (Abst. of M).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

3-Hydroxymethyl-7.beta.-(2-alkoxy-or benzyloxyimino-2-arylacetam does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3-Hydroxymethyl-7.beta.-(2-alkoxy-or benzyloxyimino-2-arylacetam, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3-Hydroxymethyl-7.beta.-(2-alkoxy-or benzyloxyimino-2-arylacetam will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-576960

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.