3-Hydroxyalkyl-3,4-dihydro-1-substituted isoquinolines

Details 3-Hydroxyalkyl-3,4-dihydro-1-substituted isoquinolines 3-Hydroxyalkyl-3,4-dihydro-1-substituted isoquinolines

1983-11-15

1985-03-12

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

564387, 564305, 2602433, 564433, 564437, 2602457, 568808, 544106, 544111, 544124, 544128, 544173, 544178, 544359, 544360, 544363, 544396, 544396, 544397, 544399, 544403, 546194, 546205, 546255, 546264, 546340, 548576, 548578, 549498, 549499, 556482, 562462, 564168, 564169, 564184, 564337, 564366, C07D21716, C07D40104

Patent

active

045046638

ABSTRACT:
The present invention concerns novel heterocyclic aminoalcoyl derivatives having the formula: ##STR1## wherein n=1, 2 or 3; A represents a nitrogen atom or the CH group, X=CH.sub.2 or CH.sub.2 O; R represents a phenyl nucleus possibly substituted; NR.sub.1 R.sub.2 =amino, methylamino, N,N-dialkylamino or an heterocyclic radical; and R.sub.3 =H, halogen, alkyl, alkyloxy or methoxy.
These derivatives are useful as drugs, especially as analgesics and antidepressants.

REFERENCES:
patent: 2168929 (1939-08-01), Bockmuhl et al.
patent: 3663608 (1972-05-01), Holava et al.
patent: 3663627 (1972-05-01), Juby et al.
patent: 3704328 (1972-11-01), Kaltenbronn
patent: 3891654 (1975-06-01), Valette
Moinet et al., "Chemical Abstracts", vol. 97, 1982, col. 216027q.

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