3-(Hydroxy or hydroxymethyl)-4-hydroxy-alpha(aminomethyl)benzyl

Details 3-(Hydroxy or hydroxymethyl)-4-hydroxy-alpha(aminomethyl)benzyl 3-(Hydroxy or hydroxymethyl)-4-hydroxy-alpha(aminomethyl)benzyl

1978-08-30

1982-06-22

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 1, 560 55, 560 56, 560 61, 560 64, 560 66, 560116, 560117, 560120, 560142, 560221, 560250, 560252, 2604055, 2604105, 424308, 424311, 424312, 424314, C07C 6976

Patent

active

043364004

ABSTRACT:
Mono-, di- and tri-esters of 3-(hydroxy or hydroxymethyl)-4-hydroxy-alpha-(aminomethyl)benzyl alcohols, obtained by methods involving reduction of the corresponding mono- and di-ester ketones, are useful for producing sympathomimetic effects, such as bronchodilation, of long duration with low cardiovascular stimulating effect, in warm-blooded mammals.

REFERENCES:
patent: 3341594 (1967-09-01), Thoma et al.
patent: 3657244 (1922-04-01), Mentrup et al.
patent: 3714229 (1973-01-01), Saari
H. Bretschneider, H., Monatsh. fur Chim. 76 368 (1947).
Von H. Bretschneider, Monatschefte fur Chemie 78 71-81 (1948).
G. Zolz, Sci. Pharm. 32 (1964) 2, 76-92.

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