3(Hydroxy or hydroxymethyl)-4(hydroxy)-.alpha.-(aminomethyl)benz

Details 3(Hydroxy or hydroxymethyl)-4(hydroxy)-.alpha.-(aminomethyl)benz 3(Hydroxy or hydroxymethyl)-4(hydroxy)-.alpha.-(aminomethyl)benz

1976-02-02

1979-02-06

Myers, Jane S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

260546, 546263, 546285, 546326, 2604105, 560 1, 560 49, 560 55, 560 61, 560100, 560105, 560106, 560107, 560108, 560117, 560138, 560221, 560252, 424305, 424309, 424310, 424311, 424314, C09F 508

Patent

active

041385810

ABSTRACT:
Mono-, di- and tri-esters of 3-(hydroxy or hydroxymethyl)-4-hydroxy-.alpha.-(aminomethyl)benzyl alcohols, obtained by methods involving reduction of the corresponding mono- and di-ester ketones, are useful for producing sympathomimetic effects, such as bronchodilation, of long duration with low cardiovascular stimulating effect, in warm-blooded mammals.

REFERENCES:
patent: 3341594 (1967-09-01), Thoma et al.
patent: 3657244 (1972-04-01), Mentrup et al.
patent: 3714229 (1973-01-01), Saari et al.
patent: 4010191 (1977-03-01), Thiele et al.
Zolss, Sci. Pharm. 32, 76-92 (1964).
Bretschneider, Montashefte fur Chemie, 76, 368-380 (1947); 77, 385-397 (1947), 78, 71-81 (1948).
Daly, J. Med. Chem. 9, 273 (1966).

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