3-Heterothio[(oxyalkyl)thioacetyl]cephalosporin derivatives

Details 3-Heterothio[(oxyalkyl)thioacetyl]cephalosporin derivatives 3-Heterothio[(oxyalkyl)thioacetyl]cephalosporin derivatives

1975-05-01

1976-11-02

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424246, C07D50150, C07D50154

Patent

active

039896960

ABSTRACT:
3-Heterothio[(oxyalkyl)thioacetyl] cephalosporin derivatives which have the formula ##EQU1## wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, tri (lower alkyl) silyl, a salt forming ion, or the group ##EQU2## R.sub.1 is hydrogen, lower alkyl, phenyl, thienyl or furyl; R.sub.2 and R.sub.6 each is hydrogen or lower alkyl; R.sub.3 and R.sub.5 is lower alkyl, phenyl or phenyl-lower alkyl; and R.sub.4 is a five- or six-member nitrogen and/or sulfur or oxygen-containing ring system; are useful as antibacterial agents.

REFERENCES:
Sassiver et al., Antimicrobial Agents & Chemotherapy 1968, pp. 101-108 (1969).

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