3-Heterothio derivatives of (formylamino)acetylamino-7-alpha-met

Details 3-Heterothio derivatives of (formylamino)acetylamino-7-alpha-met 3-Heterothio derivatives of (formylamino)acetylamino-7-alpha-met

1975-05-28

1976-12-07

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260519, 260534M, 2603322A, 424246, C07D50124, C07D50136, C07D50122

Patent

active

039962164

ABSTRACT:
3-Heterothio(formylamino)acetylamino cephalosporin derivatives of the general formula ##STR1## wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, tri(lower alkyl)silyl, trihaloethyl, a salt forming ion or the group ##STR2## R.sub.1 is hydrogen, lower alkyl, cyclo-lower alkyl, unsaturated cyclo-lower alkyl, phenyl, substituted phenyl, furyl, pyridyl or thienyl; R.sub.2 is a five or six membered nitrogen, sulfur and/or oxygen containing heterocyclic ring system; R.sub.3 is lower alkyl, phenyl or phenyl-lower alkyl; and R.sub.4 is hydrogen or lower alkyl; are useful antibacterial agents.

REFERENCES:
patent: 3766175 (1973-10-01), Lemieux et al.
patent: 3769281 (1973-10-01), Chauvette
patent: 3780037 (1973-12-01), Hazen
patent: 3819621 (1974-06-01), Morimoto et al.
patent: 3855211 (1974-12-01), Bruer et al.

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