3-Heterocyclic thiomethylcephalosporins

Details 3-Heterocyclic thiomethylcephalosporins 3-Heterocyclic thiomethylcephalosporins

1974-10-01

1976-10-12

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424246, C07D50124

Patent

active

039857395

ABSTRACT:
Cephalosporin compounds substituted at the 7-position with free or substituted .alpha.-amino or hydroxy phenylacetamido and at the 3-position with a heterocyclic thiomethyl group are prepared by displacement of a 3-acetoxymethyl compound with a mercaptoheterocycle or by 7-acylation. The products are antibacterial agents.

REFERENCES:
patent: 3516997 (1970-06-01), Takano et al.
patent: 3759904 (1973-09-01), Crast
patent: 3855213 (1974-12-01), Dunn et al.
patent: 3867380 (1975-02-01), Dunn et al.

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