[3-Heterocyclic-7-(2-methoxyimino-2-aminothiazolyl) acetamido]ce

Details [3-Heterocyclic-7-(2-methoxyimino-2-aminothiazolyl) acetamido]ce [3-Heterocyclic-7-(2-methoxyimino-2-aminothiazolyl) acetamido]ce

1978-02-14

1980-04-08

Wheeler, David E.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544 22, 544 27, 544 15, A61K 31545, C07D50120

Patent

active

041972988

ABSTRACT:
7-[2-(2-aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]cephalosporanic acid derivatives of the formula; ##STR1## wherein R.sup.1 NH is an amino group which may optionally be protected; COOR.sup.2 is a carboxyl group which may optionally be esterified; X is oxygen, sulfur or an imino group which may optionally be substituted; B is hydrogen or a hydroxyl, amino, thiol or hydrocarbon group which may optionally be substituted, or a salt thereof, are novel, .beta.-lactamase-resistant and low-toxicity compounds which display excellent activity against a broad spectrum of microorganisms including Gram-negative bacteria such as Escherichia coli, Serratia marcescens, Proteus rettgeri, Enterobacter cloacae, Citrobacter freundii. Thus, these compounds can be used for antibacterial agents in therapeutical purpose.

REFERENCES:
patent: 4033950 (1977-07-01), Cook et al.
patent: 4098888 (1978-07-01), Ochiai et al.

Affiliated with

Also associated with

Rating

[3-Heterocyclic-7-(2-methoxyimino-2-aminothiazolyl) acetamido]ce does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with [3-Heterocyclic-7-(2-methoxyimino-2-aminothiazolyl) acetamido]ce, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and [3-Heterocyclic-7-(2-methoxyimino-2-aminothiazolyl) acetamido]ce will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-973615