3-heteroaryl-3,5-dihydro-4-oxo-4H-pyridazino[4,5-b]...

Details 3-heteroaryl-3,5-dihydro-4-oxo-4H-pyridazino[4,5-b]... 3-heteroaryl-3,5-dihydro-4-oxo-4H-pyridazino[4,5-b]...

2007-06-26

2007-06-26

Habte, Kahsay (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S115000, C544S234000, C514S232800

Reexamination Certificate

active

10509695

ABSTRACT:
The invention provides compounds of general formula (I)in whichX represents a hydrogen or halogen atom; R1represents a hydrogen atom or a (C1-C4)alkyl group; R2and R3each independently of one another represent a hydrogen atom or a (C1-C4)alkyl group, or else R2and R3, together with the nitrogen atom bearing them, form a pyrrolidinyl, piperidinyl, morpholinyl or 4-(C1-C4)alkylpiperazinyl group; and Het represents a heteroaromatic group of pyridinyl, quinolinyl, isoquinolinyl, pyrimidinyl, pyrazinyl or pyridazinyl type which may carry one or more halogen atoms and/or one or more (C1-C4)alkyl and/or (C1-C4)alkoxy groups; in the form of bases, addition salts with acids, solvates or hydrates; the pharmaceutical compositions comprising them, processes for preparing them, and synthesis intermediates.

REFERENCES:
patent: 6075021 (2000-06-01), Evanno et al.
patent: 6262045 (2001-07-01), Evanno et al.
patent: 6395729 (2002-05-01), Ferzaz et al.
patent: 7109194 (2006-09-01), Burnier et al.
patent: WO 98/15552 (1998-04-01), None
patent: WO 99/06406 (1999-02-01), None
patent: WO 00/44384 (2000-08-01), None
Lacapere et al. Steroids 68 (2003) 569-585.

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