3-heteroaryl-3,5-dihydro-4-oxo-4 H...

Details 3-heteroaryl-3,5-dihydro-4-oxo-4 H... 3-heteroaryl-3,5-dihydro-4-oxo-4 H...

2008-07-22

2008-07-22

Habte, Kahsay T (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C544S248000, C544S234000

Reexamination Certificate

active

07402682

ABSTRACT:
A subject-matter of the invention is the compounds of general formula (I)in which X represents a hydrogen or halogen atom; R1represents a hydrogen atom or a (C1-C4)alkyl group; R2and R3each represent, independently of one another, a hydrogen atom or a (C1-C4)alkyl group or else R2and R3form, with the nitrogen atom which carries them, a pyrrolidinyl, piperidinyl, morpholinyl or 4-alkylpiperazinyl group; and Het represents a heteroaromatic group of pyridinyl, 1-oxidopyridinyl, quinolinyl, isoquinolinyl, pyrimidinyl, pyrazinyl or pyridazinyl type, it being possible for the heteroaromatic group to carry one or more halogen atoms and/or one or more (C1-C4)alkyl or (C1-C4)alkoxy groups; in the form of bases, of addition salts with acids, of solvates or of hydrates, the pharmaceutical compositions comprising them, processes for their preparation and synthetic intermediates.

REFERENCES:
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patent: WO 98/15552 (1998-04-01), None
patent: WO 00/44751 (2000-08-01), None
patent: WO 02/08229 (2002-01-01), None
Lacapere, J.J., et. al., Peripheral-type benzodiazepine receptor: structure and function of a cholesterol-binding protein in steroid and bile acid biosynthesis, Steroids (2003, pp. 569-585, vol. 68).

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