Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-09-16
1993-07-06
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546174, 546176, 546183, 546256, 546273, 546278, 514339, 514345, 514354, C07D40300, C07D40112, A61K 3140
Patent
active
052254216
ABSTRACT:
Compounds having the formula: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti asthmatic, anti allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.
REFERENCES:
patent: 5081138 (1992-01-01), Gillard et al.
Tetra. Lett. 24(33), 3531-2 (1983).
C.A. 84(5): 30798t (1976).
C.A. 90(19): 15920j (1979).
Fortin Rejean
Gillard John W.
Guindon Yvan
Morton Howard E.
DiPrima Joseph F.
Lopez Gabriel
Merck Frosst Canada Inc.
Springer David B.
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