3-guanidinocarbonyl-1-heteroaryl-indole derivatives,...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C544S280000

Reexamination Certificate

active

07638521

ABSTRACT:
The present invention relates to 3-guanidinocarbonyl-1-heteroaryl-indole derivatives, pharmaceutical compositions comprising such derivatives, methods of treatment comprising administering such derivatives, and processes for their preparation.

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Everett, Chris, Haemolytic disease of the newborn—time to prevent unnecessary deaths, Comparative Medicine, The British Journal of General Practice, 2000, 50 (5), p. 511.
Lauer, et al., The Synthesis of Some Chloromethoxyquinolines, J. Amer. Chem. Soc., 1946, (68) pp. 1268-1269.
Schultheis, et al., Targeted Disruption of the Murine Na+/H+ Exchanger Isoform 2 Gene Causes Reduced Viability of Gastric Parietal Cells and Loss of Net Acid Secretion, Journal Clinical Investigation, vol. 101, No. 6, Mar. 1998, pp. 1243-1253.
Toyota, et al., Tandem Michael Addition-[3,3] Sigmatropic Rearrangement Processes, Part 2. Constuction of Cyclopropa [3,4] pyrrolo [3,2-e] indol-4-one (CPI) Unit of Antitumour Antibiotic CC-1065, J. Chem. Soc. Perkin Trans. 1, (1992), (5), pp. 547-552.

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