3-fluorosulfonyloxyceph-3-em compounds

Details 3-fluorosulfonyloxyceph-3-em compounds 3-fluorosulfonyloxyceph-3-em compounds

1993-06-15

1995-05-30

Rizzo, Nicholas

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D48704, A61K 31435

Patent

active

054202698

ABSTRACT:
3-Fluorosulfonyloxyceph-3-ems having a protected amino or acylamino group in the 7-position are subject to carbon-carbon bond formation at the 3-position by means of a palladium catalyzed coupling reaction with substituted organostannanes. A process for preparing cefprozil is disclosed.

REFERENCES:
patent: 4520022 (1985-05-01), Hoshi et al.
patent: 4820816 (1989-04-01), Evans et al.
patent: 4820832 (1989-04-01), Cook et al.
patent: 4847373 (1989-07-01), Baker et al.
patent: 4870168 (1989-09-01), Baker et al.
W. J. Scott, "J. Amer. Chem. Soc.", 106 4630-4632 (1984), Palladium-Catalyzed Coupling of Vinyl Triflates with Organostannanes. A Short Synthesis of Pleraplysillin-1.
W. J. Scott, et al., "J. Amer. Chem. Soc.", 108, 3033-3040, (1986), Palladium-Catalyzed Coupling of Vinyl Triflates with Organostannanes. Synthetic and Mechanistic Studies.
J. K. Stille, et al., "J. Amer. Chem. Soc.", 109, 813-817 (1987), Stereospecific Cross-Coupling of Vinyl Halides with Vinyl Tin Reagents Catalyzed by Palladium.
American Chemical Society, 196th National Meeting, Los Angeles, CA, Sep. 25-30, 1988, Div. of Organic Chemistry, Abstract No. 32.
American Chemical Society, 196th National Meeting, Los Angeles, CA, Sep. 25-30, 1988, Div of Organic Chemistry, Abstract No. 402.

Affiliated with

Also associated with

Rating

3-fluorosulfonyloxyceph-3-em compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3-fluorosulfonyloxyceph-3-em compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3-fluorosulfonyloxyceph-3-em compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-363053