3-Ethyl-1,3-dihydro-3-methoxy-2H-indole 2-one

Details 3-Ethyl-1,3-dihydro-3-methoxy-2H-indole 2-one 3-Ethyl-1,3-dihydro-3-methoxy-2H-indole 2-one

1978-04-20

1979-10-09

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

542430, C07D20938, C07D40708

Patent

active

041705955

ABSTRACT:
The invention relates to a new and useful antibiotic substance which is of the formula ##STR1## and to processes for its production and recovery. The antibiotic which exhibits ionophoric properties, is classified as a polyether group antibiotic. The antibiotic of formula I is effective in inhibiting the growth of gram positive bacteria and exhibits utility as an antihypertensive agent and as a compound to improve ruminant feed utilization. The antibiotic of Formula I is prepared by cultivating a strain of Streptomyces sp. X-14547 in an aqueous carbohydrate solution containing nitrogenous nutrients and mineral salts and thereafter isolating the antibiotic from the fermentation broth.

REFERENCES:
patent: 4020179 (1977-04-01), Irvine
Hinman et al., J. Org. Chem., vol. 29, pp. 2431-2437 (1964).

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