3'-deoxy or 3'-O-substituted-2',5'-oligoadenylates as antiviral

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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536 256, 536 252, 514 47, A61K 3170, C07H 2102

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057007853

ABSTRACT:
Synthetic analogs of 2',5'-oligoadenylate wherein the aglycon, ribosyl moiety and/or terminal nucleoside have been modified are effective therapeutic agents, particularly against HIV infection. The analogs are utilized in compositions and methods for the treatment of disorders characterized by 2-5A pathway defects.

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