3-deoxy mycaminosyl tylonolide derivatives

Details 3-deoxy mycaminosyl tylonolide derivatives 3-deoxy mycaminosyl tylonolide derivatives

1990-09-24

1992-03-17

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 71, A61K 3170, C07H 1708

Patent

active

050968882

ABSTRACT:
3-Deoxy mycaminosyl tylonolide derivatives represented by the following general formula and salts thereof: ##STR1## wherein X represents an oxygen atom or .dbd.N--OR.sup.4 (wherein R.sup.4 represents hydrogen or lower alkyl); R.sup.1 represents a hydrogen atom, an acyl group or an alkylsilyl group; R.sup.2 represents a hydrogen atom or an acyl group; and R.sup.3 represents a hydrogen atom or a hydroxyl group. The compounds of this invention of the formula (I) are novel compounds and have excellent antibacterial activity.

REFERENCES:
patent: 4345069 (1982-08-01), Sakakibara et al.
patent: 4438109 (1984-03-01), Umezawa et al.
patent: 4794173 (1988-12-01), Umezawa et al.

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