Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus esters
Patent
1992-01-24
1993-07-13
Ramsuer, Robert W.
Organic compounds -- part of the class 532-570 series
Organic compounds
Phosphorus esters
558180, C07F 910
Patent
active
052275086
ABSTRACT:
The invention provides 3-deoxy-3-substituted analogs of phosphatidylinositol which are useful to inhibit the growth of mammalian cells, i.e., to treat neoplastic conditions and other proliferative disorders of mammalian cells.
REFERENCES:
patent: 4515722 (1985-05-01), Yang et al.
patent: 4988682 (1991-01-01), Kozikowski
patent: 5053399 (1991-10-01), Kozikowski
Martin, T. W. et al. J. Biol. Chem. 1987, 262(27), 13086-13092.
Kuksis, A. et al. Lipids 1989, 24(5), 396-407.
G. Powis et al., Cancer Chemother. Pharmacol., 29, 95 (Dec. 1991).
U. Kikkawa et al., Ann. Rev. Cell Biol., 2, 149 (1986).
M. Whitman et al., Biochim. Biophys. Acta, 948, 327 (1988).
R. F. Irvine et al., Nature, 320, 631 (1986).
Y. Nishizuka, Science, 225, 1365 (1984).
Y. Sugimoto et al., Molec. Cellular Biol., 5, 3194 (1985).
K. Fukami et al., PNAS USA, 85, 9057 (1988).
S. K. Fisher et al., J. Neurochem., 48, 999 (1987).
Y. Fukui, Oncogene Res., 4, 283 (1989).
Faug Abdul H.
Kozikowski Alan P.
Powis Garth
Tuckmantel Werner
Ambrose Michael G.
Mayo Foundation for Medical Education and Research
Ramsuer Robert W.
LandOfFree
3-deoxy-3-substituted analogs of phosphatidylinositol does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 3-deoxy-3-substituted analogs of phosphatidylinositol, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3-deoxy-3-substituted analogs of phosphatidylinositol will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2313192