Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-07-08
1990-05-15
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514277, 514334, 514336, 514357, 514269, 544333, 544335, 546256, 546257, 546258, 546283, 546284, 546335, 546341, 546342, 546268, A61K 3144, C07D21300, C07D41300, C07D21355
Patent
active
049258524
ABSTRACT:
3-Demethylmevalonic acid derivatives of the formula I (.delta.-lactone) and II (corresponding dihydroxy carboxylic acid derivative) ##STR1## in which A--B, Z, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the indicated meanings, a process for the preparation of these compounds, their use as medicaments, and pharmaceutical products, are described. In addition, new intermediates for the preparation of the compounds of the formula I and formula II are described.
REFERENCES:
Stokker et al., "Journal of Medicinal Chemistry", vol. 28, No. 3, 1985, pp. 347-358.
Bartmann Wilhelm
Beck Gerhard
Granzer Ernold
Kesseler Kurt
Hoechst Aktiengesellschaft
Lee Mary C.
Richter J.
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