3-(cyclohexanoheteroarylidenyl)-2-indolinone protein tyrosine ki

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514307, 5142352, 514339, 544144, 546200, 546201, 546164, 546165, 546172, 546173, 546175, 548455, 548460, A61K 3140, C07D20904

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061302384

ABSTRACT:
The present invention relates to novel 3-(cyclohexanoheteroarylidenyl)-2-indolinone compounds and physiologically acceptable salts and prodrugs thereof which are expected to modulate the activity of protein tyrosine kinases and therefore to be useful in the prevention and treatment of protein tyrosine kinase related cellular disorders such as cancer.

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