3-(cycloalkanoheteroarylidenyl)-2- indolinone protein tyrosine k

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514406, 514418, 514422, 514426, 548486, 5483351, 5483647, A61K 3140, A61K 31415, C07D20934, C07D23154, C07D40306

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060515937

ABSTRACT:
The present invention relates to novel 3-(cycloalkanoheteroarylidenyl)-2-indolinone compounds and physiologically acceptable salts and prodrugs thereof which are expected to modulate the activity of protein tyrosine kinases and therefore to be useful in the prevention and treatment of protein tyrosine kinase related cellular disorders such as cancer.

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