3-Condensed imidazolium-cephem compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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540222, 540225, 540227, 514203, C07D50156, A61K 31545

Patent

active

049621009

ABSTRACT:
A compound of the formula: ##STR1## wherein R.sup.1 is an amino group which may be protected, R.sup.3 is a hydrogen atom or an optionally substituted hydrocarbon residue; Z is S, S.fwdarw.O, O or CH.sub.2, R.sup.4 is a hydrogen atom, methoxy group or formamido group, R.sup.13 is a hydrogen atom, methyl group, hydroxyl group or halogen atom and A.sup..sym. is an optionally substituted imidazolium-1-yl group forming a condensed ring at the 2,3- or 3,4-position or a pharmaceutically acceptable salt or ester thereof is novel and has excellent antibacterial activity.

REFERENCES:
patent: 4665065 (1987-05-01), Miyake et al.
patent: 4788185 (1988-11-01), Miyake et al.
patent: 4826834 (1989-05-01), Yoshimura et al.
patent: 4864022 (1989-09-01), Miyake et al.

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