3-Carbamoyl-6-aminopyridinium and analogues, and their use in tr

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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546309, 546310, 536 23, 536 24, 536 26, 536 27, 536 28, 536 29, 424180, C07D21198, A61K 31455

Patent

active

043615716

ABSTRACT:
Systemic as well as topical treatment to alleviate the symptoms of skin disorders characterized by inflammation or disturbed keratinization comprising as the principal active ingredient, one or more 3-carbamoyl-6-aminopyridinium compounds, is disclosed. In the topical treatment the therapeutic composition may include one or more of the above active ingredients present in a total amount of from 0.01 to 5 percent by weight of the total composition. In the systemic treatment oral administration or parenteral injection in a total dosage of from 1 mg/kg to 50 mg/kg has been found to achieve a substantial improvement to complete remissions of the skin lesions, and to ameliorate the symptoms of arthritis that may be associated therewith.

REFERENCES:
patent: 2199839 (1940-05-01), Renshaw et al.
patent: 4067975 (1978-01-01), Yu et al.
patent: 4141977 (1979-02-01), Yu et al.

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