Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...
Patent
1990-06-29
1992-05-26
Ford, John M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Unsubstituted hydrocarbyl chain between the ring and the -c-...
540589, C07D22322
Patent
active
051169746
ABSTRACT:
New 3-carbalkoxyamino-5-aminoacyl-5H-dibenz[b,f]azepines and their pharmaceutically acceptable acid addition salts, and methods for their synthesis are described. These compounds are useful as antiarrhythmic agents in the treatment of heart disorders. The new compounds are made by reacting a 3-carbalkoxyamino-5-halogenacyl-5H-dibenz[b,f]azepines with an amine to form the desired target product, which can be optionally converted into its pharmaceutically acceptable acid addition salt.
REFERENCES:
Wunderlich et al, Pharmazie 40(12), 827-30, 1985.
Kaverina et al, Pharmazie 40(12), 830-32, 1988.
Bartsch Reni
Grizenko Anna N.
Kaverina Natalja V.
Lohmann Dieter
Lyskovzev Valentin V.
Arzneimittelwerk Dresden GmbH
Ford John M.
Gupta Y.
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