3-Benzoylfluoro-methanesulfonanilides

Details 3-Benzoylfluoro-methanesulfonanilides 3-Benzoylfluoro-methanesulfonanilides

1975-11-17

1976-11-09

Jiles, Henry R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424321, 260556A, 260570AB, C07C14374

Patent

active

RE0290327

ABSTRACT:
Benzoylhaloalkanesulfonanilides of the general type ##SPC1##
Wherein R.sub.x is a haloalkyl group having up to four carbon atoms and at least one halogen atom bonded to the alpha carbon atom or if there is no halogen bonded to said alpha carbon atom, having at least 2 halogen atoms bonded to the beta carbon atom, R is hydrogen, alkyl or alkenyl containing not more than three carbon atoms, or a pharmaceutically acceptable cation; each Y and Y' is selected from hydroxy, halogen and alkyl, alkoxy, haloalkyl and haloalkoxy groups having up to 4 carbon atoms and n and n' are each 0-3. These compounds and their salts have valuable pharmacological activity as anti-inflammatory agents.

REFERENCES:
patent: 2075359 (1937-03-01), Salzberg et al.
Rossi et al., "Annali di Chimica," vol. 56(6), June 1966, p. 733.

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