3-Benzoyl-2-nitrophenylacetic acids, metal salts, amides and est

Details 3-Benzoyl-2-nitrophenylacetic acids, metal salts, amides and est 3-Benzoyl-2-nitrophenylacetic acids, metal salts, amides and est

1979-10-18

1981-03-03

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

564166, 424319, 424324, 560 21, 562436, A61K 3124, C07C 7946

Patent

active

042541468

ABSTRACT:
3-Benzoyl-2-nitrophenylacetic acids, metal salts, amides and esters are disclosed having the formula: ##STR1## wherein R.sub.1 is hydrogen or lower alkyl; R.sub.2 is OH, OM, O-lower alkyl, NH.sub.2, NH-lower alkyl or N,N-dilower alkyl; X is hydrogen, halogen, lower alkyl, lower alkoxy, trifluoromethyl or nitro and M is a pharmaceutically acceptable cation or a fraction thereof when the cation is multivalent, hydrates thereof and n is 1-3 inclusive. The compounds have anti-inflammatory activity and methods and pharmaceutical compositions for use thereof are disclosed.

REFERENCES:
patent: 3828093 (1974-08-01), Bays et al.
patent: 4045576 (1977-08-01), Welstead, Jr. et al.
patent: 4126635 (1978-11-01), Welstead, Jr. et al.
Beilstein: Organic Chemistry 10, 361 (1910-1919).
Zinic et al., Chem. Absts., 88, 105282(p), 1978.

Affiliated with

Also associated with

Rating

3-Benzoyl-2-nitrophenylacetic acids, metal salts, amides and est does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3-Benzoyl-2-nitrophenylacetic acids, metal salts, amides and est, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3-Benzoyl-2-nitrophenylacetic acids, metal salts, amides and est will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-80155