Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1990-10-02
1992-10-06
Brown, Johnnie R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
536 26, C07H 1900
Patent
active
051533189
ABSTRACT:
The present invention relates to 3'-azido purine nucleosides and their use in medical therapy, particularly for the treatment of human immunodeficiency virus and hepatitis B virus infections, to methods for their preparation and to compositions containing them.
REFERENCES:
patent: 3929764 (1975-12-01), Fauland et al.
patent: 3983104 (1976-09-01), Vorbruggen
patent: 4724232 (1988-02-01), Rideout et al.
patent: 4880782 (1989-11-01), Eckstein et al.
E. M. Southern, J. Mol. Biol., (1975), 98, pp. 503-517, Detection of Specific Sequences Among DNA Fragments Separated by Gel Electrophoresis.
Mary Ann Sells, et al., Journal of Virology, Aug., 1988, vol. 62, No. 8, pp. 2836-2844, Replicative Intermediates of Hepatitis B Virus in HepG2 Cells that Produce Infectious Virions.
George W. J. Fleet, et al., Tetrahedron Letters, 1987, vol. 28, No. 31, pp. 3615-3618, Methyl 5-0-Tert-Butyldiphenylsilyl-2-Deoxy-D-Threo-Pentofuranoside; An Approach to the Synthesis of 3'-Substituted-2',3'-Dideoxynucleosides Including 3'-Azido-3'-Deoxythymidine and of 3'-Substituted-2',3'-Dideoxy-C-Nucleosides.
Robert W. McCollum, Viral Hepatitis, Chapter 12, pp. 327-350.
Jan S. Tuttleman, et al., Journal of Virology, Apr., 1986, vol. 58, No. 1, pp. 17-25, In Vitro Experimental Infection of Primary Duck Hepatocyte Cultures with Duck Hepatitis B Virus.
M. Imazawa, et al., J. Org. Chem., 1978, vol. 43, No. 15, Synthesis of 3'-Azido-2',3'-dideoxyribofuranosylpurines.
Ruiming Zou, et al., Communications, Jan. 6, 1987, pp. 1436-1437.
R. Cardinaud, Pyrimidine Metabolizing Enzymes, [60], pp. 446-455, 1987.
Almond Merrick R.
Collins Jon L.
Freeman George A.
Rideout Janet L.
Short Steven A.
Brown Donald
Brown Johnnie R.
Burroughs Wellcome Co.
Green Hannah O.
Nielsen Lawrence A.
LandOfFree
3'-Azido nucleoside compound does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 3'-Azido nucleoside compound, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3'-Azido nucleoside compound will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1190271