3'-azido-2',3'-dideoxy-5-methylcytidine

Details 3'-azido-2',3'-dideoxy-5-methylcytidine 3'-azido-2',3'-dideoxy-5-methylcytidine

1989-06-07

1992-01-28

Rollins, John W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 51, 424450, A61K 3170, A61K 3722

Patent

active

050844458

ABSTRACT:
The present invention is an antiviral composition which includes a means and method for delivering an HIV-inhibitory amount of an active compound of the general formula: ##STR1## wherein R is OH, monophosphate, diphosphate, or triphosphate, or a pharmacologically acceptable salt thereof; and wherein the means is a pharmaceutically acceptable carrier. In the preferred embodiment, an effective dose of 3'-azido-2',3'-dideoxy-5-methylcytidine, or its derivatives is administered in a pharmaceutically acceptable carrier to a patient for the treatment of AIDS.

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The U.S. Government has rights in this invention arising out of a Veterans Administration Merit Review Award.

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