3-arylcarbonyl-and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles

Details 3-arylcarbonyl-and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles 3-arylcarbonyl-and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles

1985-12-19

1987-01-06

Ramsuer, Robert W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

544373, 546168, 546176, 546201, 548336, 548454, 548465, 548468, 548505, C07D20912, C07D20914, C07D40310

Patent

active

046347763

ABSTRACT:
3-Arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, useful as analgesic, anti-rheumatic and anti-inflammatory agents, are prepared by reacting a 3-arylcarbonyl- or 3-cycloalkylcarbonylindole with an aminoalkyl halide in the presence of an acid-acceptor; by reacting a 1-aminoalkyl-1H-indole with an arylcarboxylic acid halide or a cycloalkanecarboxylic acid halide in the presence of a Lewis acid; or by reacting a 3-arylcarbonyl- or 3-cycloalkanecarbonyl-1-tosyloxyalkyl- or haloalkyl-1H-indole with an amine.

REFERENCES:
patent: 2930798 (1960-03-01), Schmitt
patent: 3489770 (1970-01-01), Herbst
patent: 3946029 (1976-03-01), Deschamps
Croce, Chemical Abstracts, vol. 80 (1973) No. 95655f.

Affiliated with

Also associated with

Rating

3-arylcarbonyl-and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3-arylcarbonyl-and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3-arylcarbonyl-and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-684844