3-aryl-hydroxybenzoxazines and 3,...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C544S101000, C544S105000, C514S230500

Reexamination Certificate

active

07015219

ABSTRACT:
Substituted benzoxazine and 3,4-dihydrobenzoxazine derivatives possessing activity as estrogen receptor beta (ERβ) modulators are provided which have the structure of formula Iwherein the substitutents are as described herein.In addition, a method is provided for preventing, inhibiting or treating the progression or onset of pathological conditions associated with the estrogen receptor and to pharmaceutical compositions containing such compounds.

REFERENCES:
patent: 3711478 (1973-01-01), Imscher et al.
patent: 4411890 (1983-10-01), Momany
patent: WO89/07110 (1989-08-01), None
patent: WO89/07111 (1989-08-01), None
patent: WO93/04081 (1993-03-01), None
patent: WO01/42186 (2001-06-01), None
Kuiper et al., Endocrinology, vol. 139, No. 10, 4252-4263.
The Practice of Medicinal Chemistry, Camille G. Wermuth et al., Chapter 31, 671-696 (Academic Press, 1996); Design of Prodrugs, edited by H. Bundgaard, (Elsevier, 1985).
Design of Prodrugs, edited by H. Bundgaard (Elsevier, 1985) (table of contents enclosed).
A Textbook of Drug Design and Development , P. Krogsgaard-Larson and H. Bundgaard, eds. Chapter 5, 113-191 (Harwood Academic Publishers, 1991).
Battistoni et al., Synthesis, 220-221, 1979.
Barnett et al., J.C.S. Perkin Trans. II, 747-755, 1979.
Atkinson et al., J. Org. Chem., 56, 1788-1800, 1991.
Allah et al., J. Heterocyclic Chem., 24, 1745-1748, 1987.
Edwards et al., Biorganic & Medicinal Chemistry Letters, 9, 1003-1008, 1999.
Hamann et al., J. Med. Chem., 42, 210-212, 1999.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

3-aryl-hydroxybenzoxazines and 3,... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 3-aryl-hydroxybenzoxazines and 3,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 3-aryl-hydroxybenzoxazines and 3,... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3527867

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.