3-aryl-5-alkylthio-4H-1,2,4-triazoles

Details 3-aryl-5-alkylthio-4H-1,2,4-triazoles 3-aryl-5-alkylthio-4H-1,2,4-triazoles

1991-10-04

1992-09-01

Morris, Patricia L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5482642, A61K 3141, C07D24912

Patent

active

051439336

ABSTRACT:
This invention relates to novel sulfone and sulfoxide derivatives of 3-aryl-5-alkylthio-4H-1,2,4-triazoles and to the use of 3-aryl-5-alkylthio-, alkylsulfinyl- and alkylsulfonyl-4H-1,2,4-triazoles in the treatment of patients suffering from convulsant seizures.

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patent: 4414221 (1983-11-01), Parsons et al.
G. Mazzone et al., Il Farnaco Ed. Sci, 36 (12), 1004-1018 (1981).
Joshi et al, J. Indian Chem. Soc., 51 (6), 613-5 (1974).
Russo et al, Boll. Chim. Farm, 108, 128-39 (1969).
Hoggarth, J. Chem. Soc., 1949, 1160-3.
Mhasalkar et al, J. Med. Chem., 14(3), 260-2.
Goswami et al, J. Heterocyclic Chem., 21, 1225-9 (1984).

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