Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1984-08-03
1986-12-02
Brust, Joseph Paul
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548565, A61K 3140, C07D20720
Patent
active
046265465
ABSTRACT:
The invention is concerned with partially new compounds of the general formula ##STR1## wherein R.sup.1 is a hydrogen atom or an alkyl group with up to four carbon atoms and R.sup.2 a substituted phenyl radical and the pharmacologically acceptable salts thereof.
The compounds can be prepared according to known procedures and show surprisingly a cardiovascular efficacy. They are capable of decompensating cardiac insufficiencies to a large extent. In addition to the new compounds, claim is also made for pharmaceutical compositions which contain compounds according to the general formula and their application for controlling cardiac and vascular diseases.
REFERENCES:
patent: 3644398 (1972-02-01), Helsley
patent: 3644414 (1972-02-01), Helsley
patent: 4241071 (1980-12-01), Martin et al.
Hortmann, et al., J. Org. Chem., 39, (1974), pp. 3781-3783.
Fritschi Edgar
Hartenstein Johannes
Herrmann Manfred
Mannhardt Karl
Satzinger Gerhard
Brust Joseph Paul
Daignault Ronald A.
Warner-Lambert & Company
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