Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1997-05-28
1999-03-23
Dees, Jose' G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
544114, 514252, C07D23704, A61K 3150
Patent
active
058861785
ABSTRACT:
Compounds of formula I: ##STR1## where: R.sub.10 is a group represented by formula (A), (B), or (C): ##STR2## and the other substituents are as defined in the specification; and their pharmaceutically acceptable salts are inhibitors of prostaglandin G/H synthase and are anti-inflammatory and analgesic agents.
REFERENCES:
patent: 3752826 (1973-08-01), Carson
patent: 5622948 (1997-04-01), Dunn et al.
Leuders et al., (CA 112:235333, DE 3818848).
Kim et al., (J. Pharm. Sci., vol. 83 (3), pp. 433-488, 1994).
Allen Darin A.
Dunn James P.
Sjogren Eric B.
Smith David B.
Bansal Rekha
Dees Jos,e G.
Peries Rohan
Qazi Sabiha
Syntex (U.S.A.) Inc.
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