3-aromatic and 3-heteroaromatic substituted bisnaphthalimides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514296, 544335, 546 99, 546100, A61K 31505, C07D23924, C07D40314

Patent

active

056417829

ABSTRACT:
This invention relates to 3-Pyrimidinyl Bisnaphthalimides as Anticancer Agents and pharmaceutically acceptable salts thereof, of the formula: ##STR1## and processes for the preparation of such compounds, pharmaceutical composition containing such compounds, and methods of using such compounds to treat cancer, particularly solid tumor carcinomas, in mammals.

REFERENCES:
patent: 4841052 (1989-06-01), Harnisch et al.
patent: 4874863 (1989-10-01), Brana et al.
patent: 5206249 (1993-04-01), Sun
patent: 5329048 (1994-07-01), Sun
patent: 5376664 (1994-12-01), Kaltenbach, III et al.
patent: 5416089 (1995-05-01), Patten et al.
Horiguchi et al. Bisnaphthalimido fluorescent whiteners. 1976. p. 85.

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