Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1982-07-29
1984-08-28
Rollins, Alton D.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
424250, 424263, 424270, 424258, 544366, 544369, 546153, 546172, 546176, 546269, 546274, 548186, 548189, 548262, A01N 4364, A01N 4378, C07D40506, C07D40906
Patent
active
044684045
ABSTRACT:
3-Aralkyloxy-2,3-dihydro-2-(triazolylmethyl)benzo(b)thiophenes and related derivatives having antifungal, antibacterial, and antiprotozoal activity are prepared by the reaction of the corresponding 2,3-dihydro-3-hydroxy-2-(triazolylmethyl)benzo(b)thiophene or related derivative and an aralkyl halide.
Preferred compounds are those where the aralkyl function is a hetercyclic aromatic, particularly 2-chloro-3-thenyl, and where the benzene nucleus is substituted by chlorine or fluorine.
Pharmaceutical formulations comprising compounds of this invention are described, as well as the method for their use in treating microbial infections.
REFERENCES:
patent: 3927018 (1975-12-01), Houlihan
patent: 4352808 (1982-10-01), Rane et al.
Pike Russell E.
Rane Dinanath F.
Wright John J.
Magatti Anita W.
Rollins Alton D.
Schering Corporation
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